ABSTRACT
Objective@#To explore the value of chest CT features and clinical indexes in the differential diagnosis between suspected COVID-19 with two or more negative nucleic acid tests and confirmed COVID-19.@*Methods@#The clinical data and chest CT images of 105 cases withconfirmedCOVID-19 (55 males and 50 females, aged from 2 month to 88 years) and 97 cases with suspected COVID-19(59 males and 38 females, aged from 1 month to 93 years) were analyzed retrospectively in Shiyan Taihe Hospital from January 21 to February 10, 2020. χ2test and two independent sample t test were used to analyze the clinical data and CT signs of the two cases, with P<0.05 for the difference statistically significant.@*Results@#Compared with the suspected patients, the average age of diagnosis of covid-19 was higher (t = 2.460, P = 0.01). The main pathological changes were pure ground glass (68 cases) and mixed ground glass density (53 cases) (χ2 = 50.016, P< 0.01). Interstitial thickening (83 cases) (χ2 = 55.395, P< 0.01), vascular thickening (73 cases) (χ2 = 57.527, P< 0.01), air bronchoscopic sign or bronchiectasis Zhang (67 cases) (χ2 = 17.899, P< 0.01), cord focus (54 cases) (χ2 = 5.500, P = 0.02), easily distributed under the pleura and the long axis of the lesion was parallel to the pleura (89 cases) (χ2 = 23.597, P< 0.01), most of them had no pleural effusion (χ2 = 7.017, P< 0.01); both lesions were mainly distributed in patches (89 cases were confirmed, 87 suspected) (χ2 = 19.573, P< 0.01). In addition, the lesions of patients with confirmed covid-19 showed progress in short term (72 / 87, 82.76%), and those with suspected covid-19 showed remission in short term (63 / 89, 70.78%). The difference was statistically significant (χ2 = 51.114, P< 0.01). There was no significant difference in gender and distribution of pulmonary lobes (χ2 = 1.462, P= 0.23; χ2 = 7.381, P= 0.19). The number of white blood cells (χ2 = 17.891, P< 0.01) and the percentage of lymphocytes (χ2 = 11.151,P< 0.01) of covid-19 were mostly normal or decreased, creatine kinase (χ2 = 9.589, P< 0.01) were mostly normal, and erythrocyte sedimentation rate was mostly normal or increased (χ2 = 4.240, P= 0.04).@*Conclusions@#The imaging features and biochemical indexes of diagnosed COVID-19 are different from those of suspected COVID-19. The comparative analysis of imaging features, clinical indexes and reexamination are helpful for the differential diagnosis of COVID-19 and suspected COVID-19.
ABSTRACT
Objective:To explore the value of chest CT features and clinical indexes in the differential diagnosis between suspected COVID-19 with two or more negative nucleic acid tests and confirmed COVID-19.Methods:The clinical data and chest CT images of 105 cases with confirmed COVID-19 (55 males and 50 females, aged from 2 month to 88 years) and 97 cases with suspected COVID-19 (59 males and 38 females, aged from 1 month to 93 years) were analyzed retrospectively in Shiyan Taihe Hospital from January 21 to February 10, 2020. χ 2test and two independent sample t test were used to analyze the clinical data and CT signs of the two group cases, with P<0.05 for statistically significant difference. Results:Compared with the suspected patients, the average age of confirmed ones was higher ( t=2.460, P=0.01). The main pathological changes were pure ground glass (68 cases) and mixed ground glass density (53 cases) (χ 2=50.016, P<0.01). Interstitial thickening (83 cases) (χ 2=55.395, P<0.01), vascular widening (73 cases) (χ 2=57.527, P<0.01), air bronchogram sign or bronchiectasis (67 cases) (χ 2=17.899, P<0.01), fibrous streak shadow (54 cases) (χ 2=5.500, P=0.02), commonly distributed under the pleura and the long axis of the lesion was parallel to the pleura (89 cases) (χ 2=23.597, P<0.01), most of them had no pleural effusion (χ 2= 7.017, P<0.01); both lesions were mainly distributed in patches (89 confirmed cases, 87 suspected cases) (χ 2=19.573, P< 0.01). In addition, the lesions of patients with confirmed COVID-19 showed progress in short term (72/87, 82.76%), and those with suspected COVID-19 showed remission in short term (63/89, 70.78%). The difference was statistically significant (χ 2=51.114, P< 0.01). There was no significant difference in gender and distribution of pulmonary lobes (χ 2=1.462, P=0.23; χ 2= 7.381, P=0.19). The number of white blood cells (χ 2=17.891, P<0.01) and the percentage of lymphocytes (χ 2=11.151, P<0.01) of COVID-19 were mostly normal or decreased, creatine kinase (χ 2=9.589, P<0.01) was mostly normal, and erythrocyte sedimentation rate was mostly normal or increased (χ 2=4.240, P=0.04). Conclusions:The imaging features and biochemical indexes of diagnosed COVID-19 are different from those of suspected ones. The comparative analysis of imaging features, clinical indexes and follow up examination are helpful for the differential diagnosis of COVID-19.
ABSTRACT
Objective To study the clinical value of DSA diagnosis and interventional therapy for non-neoplastic lower digestive tract hemorrhage. Methods Non-neoplastic lower digestive tract hemorrhage were diagnosed in 21 patients. Eight cases underwent embolization with gelfoam and 13 cases with infusion of pitressin. Results Intestinal angiodysplasia was found in 14 cases, colonic diverticulum in 2 and hemorrhage of unknown cause in 5. Hemorrhage in all patients was stopped after the interventional therapy with no serious complications. During the follow-up of 25～74 months, intestinal angiodysplasia bleeding recurred in 4 patients. Conclusions DSA is very helpful in the diagnosis of non-neoplastic lower digestive tract hemorrhage and interventional therapy is safe and effective for the stoppage of the bleeding.